Clinical

1. AREDS Report No. 8. A Randomized, Placebo-Controlled, Clinical trial of High-Dose Supplementation with Vitamins C and E, Beta Carotene, and Zinc for Age-Related Macular Degeneration and Vision Loss. Archives in Ophthalmology 2008;119:125-144.

2. Boyer D, Antoszyk A, Awh C, et al. Subgroup Analysis of the MARINA Study of Ranibizumab in Neovascular Age-Related Macular Degeneration. Ophthalmology 2007;114(2):246-252.

3. The Eye Diseases Prevalence Research Group. Prevalence of Age-Related Macular Degeneration in the United States. Archives in Ophthalmology 2004;122:564-572.

4. Jager R, Mieler W, Miller J. Age-Related Macular Degeneration. The New England Journal of Medicine 2008;358:2606-2617.

5. Hughes A, Orr N, Patterson C, et al. Neovascular Age-Related Macular Degeneration Risk Based on CFH, LOC387715/HTRA1, and Smoking. PLoS Medicine 2007;4(12):1993-2000.

6. Schmidt S, Hauser M, Scott W, et al. Cigarette Smoking Strongly Modifies the Association of LOC387715 and Age-Related Macular Degeneration. The American Journal of Human Genetics 2006;78:852-864.

7. Seddon J, Reynolds R, Maller J, et al. Prediction Model for Prevalence and Incidence of Advanced Age-Related Macular Degeneration Based on Genetic, Demographic, and Environmental Variables. IOVS Papers in Press. Published on December 30, 2008.

8. Swaroop A, Branham K, Chen W, et al. Genetic Susceptibility to Age-Related Macular Degeneration: A Paradigm for Dissecting Complex Disease Traits. Human Molecular Genetics 2007;16(2):R174-R182.

9. Zanke B, Hawken S, Carter R, et al. A Genetic Approach to Stratification of Risk for Age-Related Macular Degeneration. Can J Ophthalmol 2010;45:22-7.

Genetic

10. Canter J, Olson L, Spencer K, et al. Mitochondrial DNA Polymorphism A4917G is Independently Associated with Age-Related Macular Degeneration. PLoS ONE 2008;3(5):1-4.

11. Despriet D, Klaver C, Witteman J, et al. Complement Factor H Polymorphism, Complement Activators, and Risk of Age-Related Macular Degeneration. Journal of American Medical Association 2006;296(3):301-309.

12. Fritsche LG, Loenhardt T, Janssen A, Fisher SA, Rivera A, Keilhauer CN, Weber BHF: Age-related macular degeneration is associated with an unstable ARMS2 (LOC 387715) mRNA. Nature Genetics 2008:40(7) 892-896

13. Li M, Atmaca-Sonmez P, Othman M, et al. CFH Haplotypes Without the Y402H Coding Variant Show Strong Association with Susceptibility to Age-Related Macular Degeneration. Nature Genetics 2006;38(9):1049-1054.

14. Yates J, Sepp T, Matharu B, et al. Complement C3 Variant and the Risk of Age-Related Macular Degeneration. The New England Journal of Medicine 2007;357:553-561.